HealthcareBy City Prime Care Team
Stool Test or Colonoscopy: Which Colorectal Cancer Screening Is Right for You? Reading the Test Options, the Five Prep Steps and the Sample Screening Calendar
Colorectal cancer screening now starts at 45, and you have more than one choice. Compare stool tests and colonoscopy, learn how each works, how to prepare, what a positive result means, and a sample screening calendar.
Medically reviewed by City Prime Care Administrator9 min read

Table of contents
- 1. When to Start, and Who Starts Earlier
- 2. The Main Tests Compared
- 3. How Often Each Test Is Repeated
- 4. How the Stool Tests Work
- 5. How Colonoscopy Works, and the Five Prep Steps
- 6. What a Positive or Abnormal Result Means
- 7. A Sample Screening Calendar
- 8. Symptoms to Report, Red Flags, and Booking
- Conclusion
- Frequently Asked Questions
- See a Doctor in Elmhurst or Chinatown
Colorectal cancer is one of the most preventable cancers, because screening can find small growths called polyps before they turn cancerous, and can find cancer early when treatment works best. Yet many adults put screening off, often because they think the only option is a colonoscopy. In fact there are several tests, and the best one is the one you will actually do, on schedule.
This guide compares the main colorectal cancer screening tests, explains when to start, how each test works, how to prepare, what a positive result means, and gives a sample screening calendar. It draws on the preventive care, men's health, and comprehensive health assessments pages of the City Prime Care website, which say colorectal screening generally begins at 45, using a stool-based test or a colonoscopy by referral, with stool kits handled in the clinic. It is general education, not personal medical advice. You can find the clinic on Google: City Prime Care on Google. See the clinic's preventive care page.
In this article:
- 1. When to start, and who starts earlier
- 2. The main tests compared (table)
- 3. How often each test is repeated (graph)
- 4. How the stool tests work
- 5. How colonoscopy works, and the five prep steps
- 6. What a positive or abnormal result means
- 7. A sample screening calendar
- 8. Symptoms to report, red flags, and booking
1. When to Start, and Who Starts Earlier
The clinic's pages say colorectal screening generally begins at 45 for average-risk adults, which matches current U.S. Preventive Services Task Force guidance. Some people should start sooner or be screened more often, and your provider tailors the schedule to your history.
| Situation | What it may change |
|---|---|
| Average risk, age 45 to 75 | Screening is recommended; choose a test and stay on schedule |
| A parent, sibling, or child with colorectal cancer or advanced polyps | Screening may need to start earlier, often with colonoscopy; the clinic's page says a close relative with colon cancer can change when screening begins |
| Inflammatory bowel disease, such as Crohn's disease or ulcerative colitis | Surveillance colonoscopy on a specialist's schedule |
| A prior polyp or colorectal cancer | Follow-up colonoscopy as advised |
| Certain inherited conditions | Genetic counseling and earlier, more frequent testing |
| Age 76 to 85 | An individual decision with your clinician, based on health and prior screening |
For national guidance, see the U.S. Preventive Services Task Force and the CDC's colorectal cancer screening pages. Our guides on which screenings Elmhurst adults should not skip and men's checkups at every age show where colorectal screening fits.
2. The Main Tests Compared
| Test | What it is | How often | Where it is done | Pros and cons |
|---|---|---|---|---|
| 1. FIT (fecal immunochemical test) | A stool sample checked for hidden blood | Every year | At home; the clinic says stool kits can be handled in the clinic | Simple, no prep, no sedation; a positive result needs a colonoscopy; must be repeated yearly |
| 2. High-sensitivity guaiac test (gFOBT) | A stool test for hidden blood | Every year | At home | Similar to FIT with some diet or medicine limits |
| 3. Stool DNA test (such as FIT-DNA) | Looks for blood and abnormal DNA in stool | Every 1 to 3 years | At home | More sensitive for some findings but more false positives; a positive result needs a colonoscopy |
| 4. Colonoscopy | A flexible camera examines the whole colon; polyps can be removed during the test | Every 10 years if normal | Outside center by referral, as the clinic describes | Looks and treats in one test; needs bowel prep, sedation, and a ride home; small risk of complications |
| 5. Flexible sigmoidoscopy | Examines the lower colon | Every 5 years, sometimes with a yearly FIT | By referral | Less commonly used; sees only part of the colon |
| 6. CT colonography | A CT scan of the colon | Every 5 years | Imaging center by referral | No sedation; needs prep; any finding needs colonoscopy |
3. How Often Each Test Is Repeated
The graph below is an illustrative picture of how many times each test is typically done over ten years for someone with normal results, using the intervals above. Each block is one test.
| Test | Tests over 10 years (graph) | Note |
|---|---|---|
| FIT | ██████████ 10 | Every year |
| High-sensitivity guaiac test | ██████████ 10 | Every year |
| Stool DNA test | ███░░░░░░░ 3 to 10 | Every 1 to 3 years |
| Flexible sigmoidoscopy | ██░░░░░░░░ 2 | Every 5 years |
| CT colonography | ██░░░░░░░░ 2 | Every 5 years |
| Colonoscopy | █░░░░░░░░░ 1 | Every 10 years if normal |
Fewer tests do not mean a better test. The best choice depends on your risk, preferences, and willingness to repeat the test on schedule.
4. How the Stool Tests Work
A typical home stool test works like this:
- Your provider gives you a kit, or the clinic handles the kit, with clear instructions and a return method.
- At home, you collect a small stool sample using the tools in the kit, following the label exactly, and avoid urine or toilet water contamination.
- You return the sample promptly, as instructed, since samples can degrade.
- A laboratory processes it, and your provider reviews the result and tells you what it means.
- If the result is negative, you repeat the test on schedule; if positive, you need a colonoscopy to find the cause.
A positive stool test does not mean cancer. Bleeding can come from hemorrhoids, polyps, or other causes. Follow-up colonoscopy is essential, because an unfollowed positive result removes the benefit of screening.
5. How Colonoscopy Works, and the Five Prep Steps
In a colonoscopy, a specialist passes a thin, flexible camera through the rectum to look at the whole colon, usually under sedation, in about 30 to 60 minutes. Polyps are removed during the test, which is how colonoscopy prevents cancer. The clinic says colonoscopies are arranged by referral to outside specialists, and its referral team sends the order and helps with insurance approval; see our guide on when your doctor sends you to a specialist.
The five prep steps, in plain terms:
- Choose and schedule: your specialist's office gives the date, time, and instructions, and you arrange a ride home, since sedation affects driving.
- Review medicines: tell the office about blood thinners, diabetes medicines, and supplements, and ask which to hold; never stop a medicine without instruction.
- Change your diet the day before, usually clear liquids only, as directed.
- Take the bowel prep exactly as instructed, often a split dose the evening before and the morning of the test, and keep drinking clear fluids.
- Arrive on time with your ID, insurance, and a list of medicines, and plan to rest for the remainder of the day.
Many people find the prep harder than the test. Ask your clinician or the endoscopy center about options to make it easier. For background, see the MedlinePlus colonoscopy page.
6. What a Positive or Abnormal Result Means
| Result | What it generally means | Next step |
|---|---|---|
| Negative stool test | No blood or abnormal DNA found this time | Repeat on schedule |
| Positive stool test | Blood or abnormal DNA found; most positive tests do not turn out to be cancer | Colonoscopy, promptly |
| Normal colonoscopy | No polyps or cancer seen | Repeat in about 10 years if average risk |
| Polyps found and removed | Polyps are common; some can become cancer if left | Follow-up colonoscopy in a time your specialist sets, based on number, size, and type |
| Cancer found | Early-stage colorectal cancer is often highly treatable | Referral to a cancer team; your primary care clinic stays involved |
The clinic says it follows up on results and stays involved after referrals. See the American Cancer Society's colorectal cancer information for details on stages and treatment.
7. A Sample Screening Calendar
The calendar below is illustrative, not a prescription. It shows two sample paths for an average-risk adult starting at 45.
| Age | Path A: yearly FIT | Path B: colonoscopy |
|---|---|---|
| 45 | ☐ FIT | ☐ Colonoscopy |
| 46 to 54 | ☐ FIT every year (nine tests) | No test if normal |
| 55 | ☐ FIT | Repeat colonoscopy at 55 if normal |
| 56 to 64 | ☐ FIT every year | No test if normal |
| 65 | ☐ FIT | Repeat colonoscopy at 65 if normal |
| 66 to 75 | ☐ FIT every year, or switch to colonoscopy | Continue as advised |
| 76 to 85 | Individual decision | Individual decision |
Ask your clinician which path fits you and write the dates in your calendar. See also our preventive care checklist by age.
8. Symptoms to Report, Red Flags, and Booking
| Symptom or situation | Action |
|---|---|
| Blood in the stool, or black, tarry stools | Book a prompt visit; do not wait for routine screening |
| A change in bowel habits lasting more than a few weeks | Book a visit |
| Unexplained weight loss, ongoing abdominal pain, or new iron-deficiency anemia | Book a prompt visit; see why you feel tired all the time |
| Heavy rectal bleeding with dizziness or fainting | Go to the ER or call 911 |
| Severe abdominal pain or vomiting after a colonoscopy | Call the specialist or go to the ER |
| Age 45 or older and never screened | Book a visit through the appointment page |
Conclusion
The best colorectal screening is the one you will do. A yearly stool test at home or a colonoscopy every ten years both save lives, and a conversation with your clinician can match the choice to your risk and your life.
Contact Us: To ask about colorectal screening, stool test kits, or a colonoscopy referral, reach City Prime Care through our Contact Us page, or find the clinic on Google: City Prime Care on Google. This article is for general information and does not replace personal medical advice. In an emergency, call 911.
Frequently Asked Questions
See a Doctor in Elmhurst or Chinatown
Have a question about your own health? Book a visit at our Elmhurst, Queens clinic or our Chinatown, Manhattan clinic, or explore our primary care services.
Related articles
Healthcare
How Should Men Plan Their Checkups at Every Age? Reading the Age Bands, the Key Tests and the Sample Screening Calendar
From blood pressure in your twenties to colorectal, prostate, lung and aortic checks later on, men's screening needs change with age. See the essential tests by age band and a sample screening calendar.
Healthcare
How Can You Spot Skin Cancer Early? Reading the ABCDE Mole Signs, the Five Self-Check Steps and the Sample Monthly Skin-Check Log
Skin cancer is the most common cancer, and it is easiest to treat when found early. Learn the ABCDE mole signs, the main skin cancer types, a five-step self-check, a sample monthly log and when to see a doctor.
Healthcare
How Do You Protect Your Bones as You Age? Reading the Risk Factors, the Bone-Density Timeline and the Sample Bone-Health Plan
Bones thin silently, and the first sign can be a fracture. Learn the risk factors for osteoporosis, when bone density testing is recommended, calcium and vitamin D basics, and a sample bone-health plan.







